If you have survival data under constant exposure concentration,
If you measured survival only at the end of your experiment, you can use the module Surv-Standard to get a classical LC50 estimate.
If you measured survival at several time points all along your experiment:
you can use the module Surv-Standard to get a classical LC50 estimate.
you can use the module GUTS-fit to get a No-Effect-Concentration (NEC) estimate, as well as a TKTD LC50 estimate by choosing either model GUTS-RED-SD or model GUTS-RED-IT.
If you have survival data under time-variable exposure concentration, you can use the module GUTS-fit to get a No-Effect-Concentration (NEC) estimate, as well as a TKTD LC50 estimate by choosing either model GUTS-RED-SD or model GUTS-RED-IT.
In case you want to make simulations with GUTS models for different exposure scenarios, you can use the module GUTS-predict.